Patient case activity: Migraine comorbidities

Mario Peres presents a patient with migraine and comorbidities and advises how to adapt their treatment plan accordingly, addressing the complication of medication overuse.

In support of improving patient care, this activity has been planned and implemented by North American Center for Continuing Medical Education (NACCME) and Springer Healthcare IME. NACCME is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. NACCME designates this enduring activity for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This activity was launched on May 12, 2021. The data were correct at time of publication and no further updates have been made to the content

Learning objectives

After taking part in this case study, you will be able to:

  • Identify potential contraindications that should be investigated, and influence choice of acute treatment of migraine, particular focusing on underlying cardiovascular issues and medication overuse.
  • Explain how best to manage patients with migraine complicated by medication-overuse headache.

Mario Peres

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Mario Peres

Professor, Psychiatry Institute, Sao Paulo University, Sao Paulo, Brazil

Mario Peres is a neurologist, who for the past 20 years has been dedicated to headache research, clinical practice, academic training and public awareness. He is currently President of ABRACES, a Brazilian headache advocacy association, Secretary of the Brazilian Headache Society, member of the Board of Trustees of the International Headache Society, and Professor at the Psychiatry Institute, University of Sao Paulo, Brazil.


Mario Peres discloses financial support/sponsorship from Lilly, Allergan, and Novartis in speaker fees, and consultation fees from Eurofarma, Lilly, Sanofi. Peres holds patent # BR2020170233532, from INPI – Instituto Nacional da Propriedade Industrial. Registered on 30/10/2017.

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